Ankara University of Medicine

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ABSTRACT: Aim: To investigate the role of 18F-NaF PET/CT and compare it with 99m Tc-MDP body bone scintigraphy and 18F-FDG PET/CT in detecting the degree of metastatic bone tissue illness also to provide our first knowledge about 18F-NaF PET/CT inside our country. Materials and practices: A total of 37 histopathologically proven cancer tumors customers (22 male, 15 feminine) with bone tissue metastasis detected on Tc-99m MDP entire body bone tissue scan were prospectively enrolled Cebeci, following ethics committee endorsement. 18F-NaF PET/CT ended up being done on members in Ankara University Medical Faculty Nuclear drug Department for evaluation of symptomatic skeletal sites that have been bad on Tc-99m MDP whole body bone tissue scan. A lesion based comparison had been made between 18F-NaF PET/CT and Tc-99m MDP entire body bone scan per client and between 18F-NaF PET/CT and 18F-FDG PET/CT in 12/37 customers. Outcomes: The number of lesions shown by 99m Tc-MDP bone tissue scan and 18F-NaF PET/CT was equal in 4/37 (%11) regarding the situations. 18F-NaF PET/CT showed a greater number of pathological foci in 89percent of individuals. 18F-NaF PET/CT could show both lytic and blastic lesions and little lesions were much better visualized as a result of the benefit of sectional imaging with far better quality and greater target/background ratio. 18F-NaF PET/CT demonstrated a lot more metastases in 10/12 (83percent) associated with the customers when comparing to 18F-FDG PET/CT. Inside various other two patients, bone metastasis could possibly be shown only by 18F-NaF PET/CT. The uptake of 18F-FDG ended up being variable in blastic lesions and cranial bone tissue participation was missed by 18F-FDG PET/CT in some instances considering physiological brain kcalorie burning. Conclusion: Although further potential clinical studies in particular disease communities tend to be indicated to create the place of 18F-NaF PET/CT in diagnostic system, the outcomes of this pilot study from our country offer the superiority of 18F-NaF PET/CT in research of bone metastasis over 99mTc-MDP bone scan and 18F-FDG PET/CT in various malignancies. 18F-NaF PET/CT is originating ahead as an individual step bone tissue pursuing research, considering all of the advantages, but specifically prospective of detecting occult metastases and reliably directing diligent administration.

Full-text · Article · Sep 2015 · Journal of Bone Oncology

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ABSTRACT: We investigate the combined aftereffect of both homogeneous and tilted magnetic fields on energy spectrum of gapped graphene cones and long-range Coulomb impurity in framework of perturbation principle. The results illustrate the tilted magnetized field can significantly affect the spectral range of solitary particle low-energy effective Hamiltonian, besides lifting the degeneracy of angular energy channels into the existence of topological defects. The busting regarding the electron-hole symmetry by magnetic industries is explained as a direct result of sub musical organization Landau-level coupling.

Full-text · Article · Jul 2015 · Procedia - personal and Behavioral Sciences

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